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“User-friendly” is not a word that’s often used when describing marijuana edibles.

Whether you’re biting into a pot brownie cooked up in a college dorm or nibbling on a fruit chew purchased from your local dispensary, you never really know how much marijuana you’re ingesting. It can take hours to get high, and the effects can be intense and long-lasting.

That said, edibles offer a discreet way to get high in public or among disapproving company, and a single dose can power users through the worst bouts of illness-induced nausea or a marathon Netflix binge. It’s often the consumption method of choice for people using marijuana for medicinal purposes (and those who just don’t want to smoke).

Remember, it doesn’t matter who you are or what size you are. Edibles will affect everyone differently. Enjoy with caution.

Here are three things to know before you try your first marijuana edible.